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Georg (University of Minnesota)Small Molecule Probes and Leads for Male Contraception and CancerBinghe Wang9:30-10:00Take Pictures and Coffee Break10:00-10:30Zhongyin Zhang (Indiana University School of Medicine)Drugging the Undruggable: Therapeutic Potential of Targeting the Protein Tyrosine PhosphatasesXinshen Ye10:30-11:00Binghe Wang (Georgia State University)Inducing MDM2 degradation as an anticancer strategyXiaodong Shi11:00-12:30Buffet (蛻NSXChonghua Hall)June 16(Monday)Section I Organic Chemistry(O翂匰VIP Hall)Chairperson13:30-13:50Xumu Zhang (Wuhan University)Practical Catalytic HydrogenationRobin Yonggui Chi13:50-14:10Xuefeng Jiang (East China Normal University)Sulfur Atom Transfer (SAT) Reaction and Synthesis of Sulfur-Containing Drugs and Natural Products14:10-14:30Fushun Liang (Northeast Normal University)Cascade reactions of activated cyclopropanes toward aza/oxa-heterocycles14:30-14:50Robin Yonggui Chi (Nanyang Technological University)Opportunities with NHC Organocatalysis: Toward New Activation ModesXumu Zhang14:50-15:10Ang Li (Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences)Total Synthesis of Sespenine: a Bio-Inspired Aza-Prins Approach15:10-15:30Coffee Break15:30-15:50Weiping Tang (University of Wisconsin)Rh(I)-catalyzed Tandem Annulation and Cycloaddition for the Synthesis of Privileged HeterocyclesHao Xu15:50-16:10Qing Gu (Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences)Enantioselective Synthesis of Planar Chiral Ferrocenes via Pd-Catalyzed Direct C-H Bond Arylation16:10-16:30Sunliang Cui (Zhejiang University)Rh(III)-Catalyzed Cyclization and Desymmetrization for Heterocycles Synthesis16:30-16:50Hao Xu (Georgia State University)Iron-Catalyzed Nitrogen Atom Transfer for Stereoselective Difunctionalization of Unsaturated HydrocarbonsWeiping Tang16:50-17:10Bingfeng Shi (Zhejiang University)Pd-Catalyzed C (sp3)-H Bonds Functionalization: Synthetic Scope and Application17:10-17:30 Meixin Zhao (East China University of Science and Technology)Cinchona alkaloid derivatives catalyzed diastereo- and enantioselective Mannich-type reactions of isocyanoacetates with ketimines18:00-20:00Welcome Dinner Reception (蛻NSXChonghua Hall)Fengshan WangJune 17(Tuesday)Section I Organic Chemistry(O翂匰VIP Hall)Chairperson8:00-8:20Andrew Evans (Queen s University)Development of Higher-Order Carbocyclization Reactions: Emulating Terpene BiosynthesisGong Cheng8:20-8:50Yuehai Shen (Kunming University of Science and Technology)Studies towards convergent total synthesis of autolytimycin8:50-9:10Weiliang Duan (Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences)Palladium-Catalyzed Asymmetric Synthesis of Chiral Phosphorus Compounds9:10-9:30Xiaodong Shi (West Virigina University)Triazole-Gold and Triazole-Pd Pormoted CatalysisAndrew Evans9:30-9:50Renhua Fan (Fudan University)Break and Rebuild the Aromaticity:Application of Dearomatization Strategy in the Synthesis of Heterocyclic Compounds9:50-10:10Zhihui Shao (Yunnan University)Structural Unit-Directed Asymmetric Catalysis and Divergent Total Synthesis10:10-10:30Coffee Break10:30-10:50Gong Cheng (Penn State University)Development of Useful C-H Functionalization Chemistry for Organic SynthesisXiaodong Shi10:50-11:10Hegui Gong (Shanghai University)Ni-catalyzed reductive coupling of tertiary alkyl halides11:10-11:30Shouyun Yu (Nanjing University)De novo synthesis of nitrogen aromatic compounds enabled by somophilic isocyanide insertions11:30-11:50Shuanhu Gao (East China Normal University)Total Synthesis of Bioactive Natural Products: Taiwaniaquinol B and Gracilamine12:00-13:00Buffet (蛻NSXChonghua Hall)June 17(Tuesday)Section I Organic Chemistry(馼S|i踁|iO畫The 4th Floor Meeting Room, Gongbei Building)Chairperson13:30-13:50Lei Liu (Shandong University)Catalytic enantioselective C-H functionalization of heterocyclesZhenghu Xu13:50-14:10Jian Xiao (Qingdao Agricultural University)sp3 C-H functionalization of azarenes under metal free and catalyst free conditions14:10-14:30Huadong Xu (Changzhou University)A novel cyclization/aza-Claisen rearrangement cascade initiated by ketenimine formation: highly efficient synthesis of -allyl cyclic amidines14:30-14:50Zhenghu Xu (Shandong University)Tandem Metal Relay Catalysis for HeterocyclesLei Liu14:50-15:10Zhenghui Guan (Northwest University)Synthesis of azaheterocycles via cyclization of enamides and alkynes15:10-15:30Shifa Zhu (South China University of Technology)Transition Metal-Catalyzed Generation and Trapping of the o-QDMs: The Applications in the Diels-Alder reactions15:30-15:50Xu Cheng (Nanjing University)Enantioselective Construction of Chiral Carboniolamide16:00-16:30Closing Ceremony(馼S|i踁|iO畫The 4th Floor Meeting Room, Gongbei Building)Hao Fang18:00-19:00Buffet (蛻NSXChonghua Hall)June 16(Monday)Section II Bioorganic Chemistry(O寘SMeeting Hall)Chairperson13:30-13:50Zhongwu Guo (Wayne State University)Synthesis and Biological Studies of GPI Anchors and GPI-Anchored ProteinsXiangming Guan13:50-14:10Yu Rao (Tsinghua University)Developing Novel Chemical Probes for Early Drug Discovery14:10-14:30Zheng Yin (Nankai University)Discovery of Enterovirus 71 3C Protease Inhibitors14:30-14:50Xiangming Guan (South Dakota State University)A combined inhibition of lactate dehydrogenase and pyruvate dehydrogenase kinase through the use of oxamate and dichloroacetate, and their prodrugs as a novel approach for cancer growth inhibitionZhongwu Guo14:50-15:10Xichen Lin GSK China Identification of S1P1 Agonists for the Treatment of Multiple Sclerosis15:10-15:30Coffee Break15:30-15:50Yujun Zheng (The University of Georgia)Bioorthogonal Chemical Probes of Protein Lysine AcetyltransferasesWenfang Xu15:50-16:10Zongbao Zhao (Dalian Institute of Chemical Physics, Chinese Academy of Sciences)Protein methylation in yeast16:10-16:30Qingsong Liu (High Magnetic Field Laboratory, Chinese Academy of Sciences)Discovery of a super potent BTK kinase inhibitor which induce strong protein degradation16:30-16:50Li Niu (University at Albany, State University of New York)Developing chemical inhibitors and RNA aptamers against AMPA receptor channelsXinyong Liu16:50-17:10Peng ChenPeking University Deprotection Chemistry-mediated Protein Activation in Living Cells17:10-17:30 Yi Tang (University of California, Los Angeles)Exciting New Enzymes from Fungal Biosynthetic Pathways18:00-20:00Welcome Dinner Reception (蛻NSXChonghua Hall)Fengshan WangJune 17(Tuesday)Section II Bioorganic Chemistry(O寘SMeeting Hall)Chairperson8:00-8:20Bin Xu (Virginia Tech)Molecular Mechanisms of Amylin as a Novel Contributor to Alzheimer s Disease and Natural Product Inhibitor Discovery Qian Wang8:20-8:50Haibing Zhou (Wuhan University)Novel Selective Estrogen Receptor Modulators (SERMs): Protein-Ligand Interactions and the Dual Regulation Mechanism Study8:50-9:10Luqing Shang (Nankai University)Discovery of anti-HCV Agents9:10-9:30Qian Wang (University of South Carolina)Probing reversible click reactions at the single-molecule levelDiwan S Rawat9:30-9:50Xiaohua Peng (University of Wisconsin Milwaukee)Inducible DNA Cross-Linking Agents as Selective Anticancer Drugs 9:50-10:10Wei Li (University of Tennessee Health Science Center)Discovery of novel tubulin inhibitors for metastatic melanoma10:10-10:30Coffee Break10:30-10:50Diwan S Rawat (University of Delhi)Identification of Lead Antimalarial Through Rational Drug DesignBin Xu10:50-11:10Bingui Wang (Institute of Oceanology, Chinese Academy of Sciences)In vitro and in vivo anticancer evaluation of norditerpenoids from the marine alga-derived endophytic fungus Aspergillus wentii 11:10-11:30Dianqing Sun (University of Hawaii at Hilo)Natural Product-Inspired Novel Antibacterial Agents11:30-11:50Bin He (Guiyang Medical University)Development of Mechanism-based Inhibitors for Sirtuins12:00-13:00Buffet (蛻NSXChonghua Hall) 16:00-16:30Closing Ceremony (馼S|i踁|iO畫The 4th Floor Meeting Room, Gongbei 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la!yt$-N奣????%5&5*5-595:5?46l6?????????????缲咆柏熦弨嘏豯嘏豜豎豎豎h7ZMCJOJQJaJh7ZMCJOJQJ^JaJo('hh HCJOJQJaJmHnHuh襳h襳CJOJQJaJhh HCJOJQJaJo( hh HCJOJQJ^JaJ)hh HB*CJKHOJQJaJph%hh HB*CJOJQJaJphhh HCJOJQJaJ/hh H5丆JPJ^JaJmH nHsH tH????C4( $$Ifa$gd H$d$Ifa$gd$-Nkd?$$IfT杔攳諪?g €q  t靠靠靠?6    44 la!p靠靠靠yt聾?奣?&5-5.5:5}5J;/ $$Ifa$gd襳$d$Ifa$gd濬nkd鼹$$IfT杔4攳諪?g q t?6    44 la!yt$-N奣$d$Ifa$gd$-N$$1$Ifa$gd H}5?566p6??Lkd嘻$$IfT杔4攳諪?g q t?6    44 la!yt$-N奣$d$Ifa$gd$-N $$Ifa$gd H???<7??gXG;X $$Ifa$gd H$$7$8$H$Ifa$gd H$d$Ifa$gd$-Nkd?$$IfT杔4攳諪?g q t?6    44 la!yt$-N奣?????gXL=$d$Ifa$gd$-N $$Ifa$gd$-N$d$Ifa$gd7ZMkd}=$$IfT杔4攳諪?g q t?6    44 la!yt$-N奣?????888:8<8V8Z8????????9褶裣么ù晛q暣d胐TE2$h8Jhy CJKHOJQJ^JaJh8Jhy CJOJQJaJhhy CJOJQJaJo(hy CJOJQJaJo(h?CJKHOJQJ^JaJ'hcsh?CJH*KHOJQJ^JaJ$hcsh?CJKHOJQJ^JaJhACJOJQJaJhhy CJOJQJaJhy CJOJQJaJhh HCJOJQJaJ$h8Jh8JCJKHOJQJ^JaJh8Jh8JCJOJQJaJ??8?C0$ $$Ifa$gdA$d$Ifa$gd聾?kdT>$$IfT杔攳諪?g €q  t靠靠靠?6    44 la!p靠靠靠yt聾?奣????4!$d$Ifa$gdy kdn?$$IfT杔攳諪?g €q  t靠靠靠?6    44 la!p靠靠靠yt聾?奣$d$Ifa$gd聾?99 9999&9.909<9>9@9V9????疋杖顶枆杴m]M>+>$h h CJKHOJQJ^JaJh h?LCJOJQJaJh h?LCJOJQJ\乤Jh h CJOJQJ\乤Jhh?LCJOJQJaJo(h CJOJQJaJh CJOJQJaJo(hh?LCJOJQJaJ hh?LCJOJQJ^JaJ#hdhCJOJQJ^JaJo(h颲CJOJQJaJo(h乷CJOJQJaJo(hhy CJOJQJaJh8Jhy CJOJQJaJ?9 9 9(kd園$$IfT杔攳諪?g €q  t靠靠靠?6    44 la!p靠靠靠yt聾?奣$d$Ifa$gd$-N $$Ifa$gd聾? 9999999999.9@9???$d$Ifa$gdA$d$Ifa$gd?L$剟d$IfUD?]剟a$gd?Ldgd颲??-E6(($$1$Ifa$gd?L$d$Ifa$gd$-Nkd$$IfT杔諪?g €q  t靠靠靠?6    44 la!p靠靠靠yt聾?奣??:-=>KLPQTUVXYZmno疋噔蒜蒜糕糕р椻嬧_Ph$-NCJOJQJ^JaJo(h1CJOJQJ^JaJo(h1CJOJQJ^JaJo(h鎆CJOJQJ^JaJh鎆CJOJQJaJhh$-NCJOJQJaJo( hh$-NCJOJQJ^JaJ%hh$-NB*CJOJQJaJph)hh$-NB*CJKHOJQJaJphUhh$-NCJOJQJaJhh?LCJOJQJaJWenfang Sun (North Dakota State University)Heteroleptic cationic iridium complexes: Synthesis, photophysics and nonlinear absorptionGuijun Wang13:50-14:10Yonghai Chai (Shanxi Normal University)New type of aza-MBH reaction and its application to one-pot efficient synthesis of highly substituted dihydropyrroles14:10-14:30Guangxi Zhai (Shandong University)Hyaluronic acid-quercetin conjugate micelles: Synthesis, characterization, in vitro and in vivo evaluation14:30-14:50Guijun Wang (Old Dominion University)Design, synthesis, and characterization of a series of functional glycoclustersWenfang Sun14:50-15:10Jun Li (National University of Singapore)Smart Supramolecular Nano Drug/Gene Carriers Self-Assembled from Functional Polymers15:10-15:30Coffee Break15:30-15:50Xiaogang Liu (National University of Singapore)Upconversion Nanocrystals: A New Class of Luminescent BioprobesLiang Xue15:50-16:10Wei Zhang (University of Colorado Boulder)Novel Shape-Persistent Organic Molecular Cages and Their Biological Activity16:10-16:30Yongsheng Zhao (Institute of Chemistry, Chinese Academy of Sciences)Organic Nanophotonic Materials and Devices16:30-16:50Liang Xue (University of the Pacific)Targeting Telomeric G-quadruplex DNA with Phenanthroline Based Metal ComplexesXiaogang Liu16:50-17:10Jia Sheng (University at Albany, State University of New York)Crystal Structure Studies of 2?5?linked RNA17:10-17:30 Guodong Liu (North Dakota State University)Nucleic Acid-Based Lateral Flow Biosensors for Biomedical and Environmental Applications17:30-17:50Yaoqun Li (Xiamen University)Hot-spot surface plasmon-coupled directional emission and its biosensing applications18:00-20:00Welcome Dinner Reception (蛻NSXChonghua Hall)Fengshan WangJune 17(Tuesday)Section III Materials and Applied Chemistry(,{mQO畫No.6 Conference Room)Chairperson8:00-8:20Jian Liu (University of North Carolina)Chemoenzymatic synthesis of low molecular weight heparinsHaoru Sun8:20-8:50Yongshu Xie (East China University of Science and Technology)Ion probes based on linear and macrocyclic polypyrroles8:50-9:10Jiayu Zhou (Shimadzu China)癳媁貧He貧瘇墊+gS€b/g(C2P)(u嶯Sf[Tbir蔛)Y6qir剉瘇SNr^錻9:10-9:30Haoran Sun (University of South Dakota)Fluorinated Materials for a Sustainable World: from Energy Harvesting and Storage to Biomedical ApplicationsLixin Zhang9:30-9:50Hongzhi Cao (Shandong University)Substrate engineering directed chemoenzymatic synthesis of sialosides9:50-10:10Chu Wang (Peking University)A Chemoproteomic Platform to Quantitatively Map Targets of Lipid-derived Electrophiles10:10-10:30Coffee Break10:30-10:50Lixin Zhang (Institute of Microbiology, Chinese Academy of Sciences)Bioprospecting Novel Marine Natural Products for Potential Anti-infective Drugs Jian Liu10:50-11:10Xinjing Tang (Peking University)Bioorthogonal SERS Nanoprobes for Tumor Targeting and Spectroscopic Detection11:10-11:30Qianbin Li (Central South University)Novel anti-NSCLC strategy: Dual inhibition of RAF/MEK/ERK and PI3K/AKT/mTOR signaling pathways with small molecules11:30-11:50Yawen Wang (Lanzhou University)Merging of Supramolecular Chemistry Approach and Specific Reactions: Development of Several Fluorescent Chemosensors and 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